The skeleton: the new controller of male fertility?

Lee B Smith; Philippa T K Saunders

doi:10.1016/j.cell.2011.02.028

The skeleton: the new controller of male fertility?

Cell. 2011 Mar 4;144(5):642-3. doi: 10.1016/j.cell.2011.02.028.

Authors

Lee B Smith¹, Philippa T K Saunders

Affiliation

¹ MRC Centre for Reproductive Health, The University of Edinburgh, The Queen's Medical Research Institute, 47 Little France Crescent, Edinburgh EH16 4TJ, UK.

PMID: 21376228
DOI: 10.1016/j.cell.2011.02.028

Abstract

Sex steroids, including testosterone, regulate the development and function of the male skeleton. Oury et al. (2011) identify a surprising new connection between the skeleton and the testis, which has implications for male fertility. They show that testosterone production in the testis is directly influenced by the bone-derived hormone osteocalcin.

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