Serotonin-specific drugs for anxiety and depressive disorders

Annu Rev Med. 1990:41:437-46. doi: 10.1146/annurev.me.41.020190.002253.

Abstract

In the last few years there has been a marked increase in knowledge regarding the possible roles of serotonin neuronal dysfunction in the pathophysiology and treatment of anxiety and depressive disorders. During the same time period, new drugs with specific actions on serotonin function have become available for clinical testing. This review provides an update on the efficacy of serotonin-specific drugs for anxiety and depressive disorders.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.
  • Research Support, U.S. Gov't, P.H.S.
  • Review

MeSH terms

  • Anxiety Disorders / drug therapy*
  • Depressive Disorder / drug therapy*
  • Humans
  • Neurotransmitter Uptake Inhibitors / therapeutic use*
  • Receptors, Serotonin / drug effects*
  • Serotonin / physiology*
  • Serotonin Antagonists / therapeutic use*

Substances

  • Neurotransmitter Uptake Inhibitors
  • Receptors, Serotonin
  • Serotonin Antagonists
  • Serotonin