Elegant metabolite biosynthesis

Adam C Jones; Emily A Monroe; William H Gerwick

doi:10.1016/j.chembiol.2011.03.001

Elegant metabolite biosynthesis

Chem Biol. 2011 Mar 25;18(3):281-3. doi: 10.1016/j.chembiol.2011.03.001.

Authors

Adam C Jones¹, Emily A Monroe, William H Gerwick

Affiliation

¹ Center for Marine Biotechnology and Biomedicine, Scripps Institution of Oceanography and Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, La Jolla, CA 92093, USA.

PMID: 21439471
DOI: 10.1016/j.chembiol.2011.03.001

Abstract

Hormaomycin, an NRPS-produced bacterial metabolite involved in microbial signaling, possesses several remarkable structural features. The study by Höfer et al. (2011) employed a range of methodologies to explore and ultimately understand the elaborate biosynthesis of this complex natural product.

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