Whole-genome sequences of four Mycobacterium bovis BCG vaccine strains

J Bacteriol. 2011 Jun;193(12):3152-3. doi: 10.1128/JB.00405-11. Epub 2011 Apr 8.

Abstract

Mycobacterium bovis Bacille Calmette-Guérin (BCG) is the only vaccine available against tuberculosis (TB). A number of BCG strains are in use, and they exhibit biochemical and genetic differences. We report the genome sequences of four BCG strains representing different lineages, which will help to design more effective TB vaccines.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • BCG Vaccine*
  • Gene Deletion
  • Gene Duplication
  • Gene Expression Regulation, Bacterial / physiology
  • Genetic Variation
  • Genome, Bacterial*
  • Molecular Sequence Data
  • Mycobacterium bovis / classification*
  • Mycobacterium bovis / genetics*

Substances

  • BCG Vaccine

Associated data

  • GENBANK/AEZE00000000
  • GENBANK/AEZF00000000
  • GENBANK/AEZG00000000
  • GENBANK/AEZH00000000