Skeletal recovery from hepatitis C-associated osteosclerosis (HCAO) following antiviral treatment

Joint Bone Spine. 2011 Jul;78(4):409-11. doi: 10.1016/j.jbspin.2011.02.016. Epub 2011 Apr 17.

Abstract

Hepatitis C-associated osteosclerosis (HCAO) is characterized by increased bone mass following hepatitis C infection. We report here a case of HCAO that lasted 8 years before the patient received antiviral hepatitis treatment. Seven years after the antiviral treatment, the evolution of radiographs and densitometry showed skeletal recovery of osteosclerosis. This case strengthens the relationship between viral infection and osteosclerosis.

Publication types

  • Case Reports

MeSH terms

  • Antiviral Agents / therapeutic use
  • Bone and Bones / diagnostic imaging
  • Bone and Bones / pathology*
  • Female
  • Hepatitis C, Chronic / complications*
  • Hepatitis C, Chronic / drug therapy
  • Hepatitis C, Chronic / pathology*
  • Humans
  • Interferons / therapeutic use
  • Middle Aged
  • Osteosclerosis / diagnostic imaging
  • Osteosclerosis / etiology*
  • Osteosclerosis / pathology*
  • Radiography
  • Recovery of Function
  • Ribavirin / therapeutic use

Substances

  • Antiviral Agents
  • Ribavirin
  • Interferons