Effective dose evaluation for BNCT treatment in the epithermal neutron beam at THOR

J N Wang; C K Huang; W C Tsai; Y H Liu; S H Jiang

doi:10.1016/j.apradiso.2011.04.009

Effective dose evaluation for BNCT treatment in the epithermal neutron beam at THOR

Appl Radiat Isot. 2011 Dec;69(12):1850-3. doi: 10.1016/j.apradiso.2011.04.009. Epub 2011 Apr 16.

Authors

J N Wang¹, C K Huang, W C Tsai, Y H Liu, S H Jiang

Affiliation

¹ Department of Engineering and System Science, National Tsing Hua University, Hsinchu, Taiwan.

PMID: 21530281
DOI: 10.1016/j.apradiso.2011.04.009

Abstract

This paper aims to evaluate the effective dose as well as equivalent doses of several organs of an adult hermaphrodite mathematical phantom according to the definition of ICRP Publication 60 for BNCT treatments of brain tumors in the epithermal neutron beam at THOR. The MCNP5 Monte Carlo code was used for the calculation of the average absorbed dose of each organ. The effective doses for a typical brain tumor treatment with a tumor treatment dose of 20 Gy-eq were evaluated to be 0.59 and 0.35 Sv for the LLAT and TOP irradiation geometries, respectively. In addition to the stochastic effect, it was found that it is also likely to produce deterministic effects, such as cataracts and depression of haematopoiesis.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Boron Neutron Capture Therapy*
Brain Neoplasms / radiotherapy
Humans
Monte Carlo Method