Development of a phenotypic method for detection of fecal carriage of OXA-48-producing enterobacteriaceae after incidental detection from clinical specimen

J Clin Microbiol. 2011 Jul;49(7):2761-2. doi: 10.1128/JCM.00055-11. Epub 2011 May 11.

Abstract

We report incidental isolation of an OXA-48-producing Escherichia coli strain in urine of a 62-year-old woman recently returning from a 2-month vacation in Morocco. Commercially available extended-spectrum beta-lactamase (ESBL)-targeting medium failed to detect it in the patient's stools, although a locally developed and easy-to-implement method using ertapenem-supplemented brain heart infusion (BHI) broths could.

Publication types

  • Case Reports
  • Evaluation Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / metabolism*
  • Anti-Bacterial Agents / pharmacology*
  • Escherichia coli / enzymology*
  • Escherichia coli / isolation & purification
  • Female
  • Humans
  • Microbial Sensitivity Tests / methods
  • Middle Aged
  • Morocco
  • Sensitivity and Specificity
  • Urine / microbiology
  • beta-Lactam Resistance*
  • beta-Lactamases / metabolism*
  • beta-Lactams / metabolism*
  • beta-Lactams / pharmacology*

Substances

  • Anti-Bacterial Agents
  • beta-Lactams
  • beta-Lactamases