Stepwise assembly of metal-organic framework based on a metal-organic polyhedron precursor for drug delivery

Hai-Ning Wang; Xing Meng; Guang-Sheng Yang; Xin-Long Wang; Kui-Zhan Shao; Zhong-Min Su; Chun-Gang Wang

doi:10.1039/c1cc11932j

Stepwise assembly of metal-organic framework based on a metal-organic polyhedron precursor for drug delivery

Chem Commun (Camb). 2011 Jul 7;47(25):7128-30. doi: 10.1039/c1cc11932j. Epub 2011 May 26.

Authors

Hai-Ning Wang¹, Xing Meng, Guang-Sheng Yang, Xin-Long Wang, Kui-Zhan Shao, Zhong-Min Su, Chun-Gang Wang

Affiliation

¹ Institute of Functional Material Chemistry, Department of Chemistry, Northeast Normal University, Changchun 130024, PR China.

PMID: 21614372
DOI: 10.1039/c1cc11932j

Abstract

A 12-connected network with fcu topology was firstly reported focusing on using predesigned metal-organic polyhedron (MOP) as the precursor, and its adsorption and delivery of the drug 5-fluorouracil (5-FU) was also determined.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Drug Carriers / chemistry*
Fluorouracil / chemistry
Models, Molecular
Molecular Conformation
Organometallic Compounds / chemistry*

Substances

Drug Carriers
Organometallic Compounds
Fluorouracil