Synthesis of uniformly 13C-labeled polycyclic aromatic hydrocarbons

Org Biomol Chem. 2011 Aug 7;9(15):5431-5. doi: 10.1039/c0ob01107j. Epub 2011 Jun 13.

Abstract

Convergent synthetic pathways were devised for efficient synthesis of a series of uniformly (13)C labeled polycyclic aromatic hydrocarbons de novo from U-(13)C-benzene and other simple commercially-available (13)C-starting compounds. All target products were obtained in excellent yields, including the alternant PAH U-(13)C-naphthalene, U-(13)C-phenanthrene, U-(13)C-anthracene, U-(13)C-benz[a]anthracene, U-(13)C-pyrene and the nonalternant PAH U-(13)C-fluoranthene.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Anthracenes / chemical synthesis
  • Anthracenes / chemistry
  • Carbon Isotopes
  • Molecular Structure
  • Naphthols / chemical synthesis
  • Naphthols / chemistry
  • Polycyclic Aromatic Hydrocarbons / chemical synthesis*
  • Polycyclic Aromatic Hydrocarbons / chemistry
  • Polycyclic Compounds / chemical synthesis*
  • Polycyclic Compounds / chemistry

Substances

  • Anthracenes
  • Carbon Isotopes
  • Naphthols
  • Polycyclic Aromatic Hydrocarbons
  • Polycyclic Compounds
  • anthracene