Diet, physical, and biochemical characteristics of children and adolescents with type 1 diabetes: relationship between dietary fat and glucose control

Pediatr Diabetes. 2012 Mar;13(2):137-46. doi: 10.1111/j.1399-5448.2011.00781.x. Epub 2011 Jun 15.

Abstract

Background: Nutritional habits may significantly influence glycemic control and cardiovascular risk factors in youth with type 1 diabetes (T1D).

Aims: To assess dietary intake, cardiovascular risk factors, and the association between diet composition and glycemic control in Italian youth with T1D.

Methods: Subjects included 114 youth aged 6-16 yr with T1D receiving a routine treatment program with nutrition counseling and 448 controls. Cross-sectional measures included dietary intake, anthropometry, blood pressure, lipid profile, and, in children with diabetes, HbA1c.

Results: In prepubertal children, BMI, subcutaneous skinfolds, the prevalence of overweight/obesity, and LDL cholesterol (LDL-CH) were significantly lower in patients than in controls, whereas HDL cholesterol (HDL-CH) was higher. Pubertal boys with T1D did not differ significantly from controls in either anthropometry or lipid profile. Pubertal girls with T1D had a higher BMI and higher triceps skinfolds than controls but not significantly different prevalence of overweight/obesity or lipid profile. Compared to controls, participants with T1D had a lower intake of lipids and simple carbohydrates, a higher ratio of unsaturated/saturated fats and fibre, and a dietary intake closer to the National Reference Dietary Intakes (RDIs). The odds of having an HbA1c higher than 7.5, adjusted for BMI, lipid, and fibre intake, increases by 53% for every 1% increase of energy intake from saturated fat in the diet and by 30% for every year of duration of diabetes.

Conclusions: Youth with T1D having regular nutritional counseling had a diet closer to RDIs than controls and not different cardiovascular risk factors. High saturated fatty acid intake was associated with poor blood glucose control.

MeSH terms

  • Adolescent
  • Blood Glucose / metabolism*
  • Blood Pressure
  • Body Mass Index
  • Child
  • Cholesterol, HDL / blood
  • Cholesterol, LDL / blood
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 1 / blood
  • Diabetes Mellitus, Type 1 / epidemiology*
  • Diet / statistics & numerical data*
  • Dietary Fats / blood*
  • Energy Intake
  • Female
  • Glycated Hemoglobin / analysis
  • Humans
  • Italy / epidemiology
  • Lipids / blood
  • Male
  • Overweight / epidemiology
  • Prevalence
  • Skinfold Thickness

Substances

  • Blood Glucose
  • Cholesterol, HDL
  • Cholesterol, LDL
  • Dietary Fats
  • Glycated Hemoglobin A
  • Lipids
  • hemoglobin A1c protein, human