Novel CUX1 missense mutation in association with 7q- at leukemic transformation of MPN

Am J Hematol. 2011 Aug;86(8):703-5. doi: 10.1002/ajh.22069. Epub 2011 Jun 14.
No abstract available

Publication types

  • Multicenter Study
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adaptor Proteins, Signal Transducing
  • Adaptor Proteins, Vesicular Transport / genetics
  • Chromosome Deletion
  • Chromosomes, Human, Pair 7 / genetics
  • Cytogenetic Analysis
  • Genetic Association Studies
  • Homeodomain Proteins / genetics*
  • Humans
  • Leukemia, Myeloid, Acute / complications
  • Leukemia, Myeloid, Acute / genetics
  • Loss of Heterozygosity
  • Mutation, Missense*
  • Myeloproliferative Disorders / complications
  • Myeloproliferative Disorders / genetics*
  • Nuclear Proteins / genetics*
  • Oligonucleotide Array Sequence Analysis
  • Polymorphism, Single Nucleotide
  • Primary Myelofibrosis / complications
  • Primary Myelofibrosis / genetics
  • Protein Structure, Tertiary
  • Repressor Proteins / genetics*
  • Transcription Factors
  • Transformation, Genetic*

Substances

  • Adaptor Proteins, Signal Transducing
  • Adaptor Proteins, Vesicular Transport
  • CUX1 protein, human
  • Homeodomain Proteins
  • Nuclear Proteins
  • Repressor Proteins
  • SH2B2 protein, human
  • Transcription Factors

Supplementary concepts

  • Chromosome 7, monosomy