[Salivary gland tumors in children]

Bull Cancer. 2011 Jul;98(7):847-55. doi: 10.1684/bdc.2011.1399.
[Article in French]

Abstract

Salivary gland tumors in children are rare: they correspond to 8-10% of head and neck pediatric tumors. Clinicians of all disciplines should be aware of this diagnosis in front of non-inflammatory mass of the parotid or in the territory of other salivary glands. In children, 50% of salivary gland tumors are malignant which contrasts with a 10-25% risk in adults. Epithelial tumors are the most common, mucoepidermoïd carcinomas of the parotid in particular. Surgery is the treatment of choice in epithelial tumors. Adjuvant radiotherapy may be indicated in case of unfavorable prognostic factors but must be balanced with the risk of radiation-induced growth defects and secondary cancer. The role of chemotherapy is limited in these tumors, but should be discussed in case of an inoperable or metastatic lesion.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Adolescent
  • Child
  • Diagnosis, Differential
  • Humans
  • Rare Diseases* / classification
  • Rare Diseases* / diagnosis
  • Rare Diseases* / pathology
  • Rare Diseases* / therapy
  • Salivary Gland Neoplasms* / classification
  • Salivary Gland Neoplasms* / diagnosis
  • Salivary Gland Neoplasms* / pathology
  • Salivary Gland Neoplasms* / therapy