Transvaginal mesh surgery for pelvic organ prolapse--Prolift+M: a prospective clinical trial

Int Urogynecol J. 2011 Nov;22(11):1405-11. doi: 10.1007/s00192-011-1482-4. Epub 2011 Jul 1.

Abstract

Introduction and hypothesis: This study deals with assessment of safety, efficacy, and potential complications of Prolift+M system to correct uterovaginal prolapse.

Methods: We analyzed a prospective cohort treated with the Gynecare PROLIFT+M mesh system between October 2008 and March 2010. A composite score that included subjective/objective cure and lack of complications was used to assess treatment success.

Results: One hundred sixty-seven women (age 65.1 ± 11.2 years, BMI 29.2 ± 5.8 kg/m(2)) were treated for pelvic organ prolapse using the PROLIFT+M system. Seven anterior Prolift+M, 42 posterior Prolift+M, and 118 total Prolift+M mesh surgeries were performed in patients with stage II or greater degrees of prolapse. Mean operative time was 122.7 ± 43.9 min. Mean intraoperative blood loss was 119.4 ± 125.3 ml. Our composite success score was 72.5% (treatment failures per POP-Q stage 1.4%, perception of bulge 4.4%, erosions 3.6%, pain/dyspareunia 3.7%, incontinence 0.7%, de novo urge urinary incontinence 8.7%, voiding dysfunction 0.6%, recurrent urinary tract infection 2.2%, and anal incontinence 2.2%).

Conclusions: Prolift+M surgery is safe and effective with minimal postoperative morbidities.

Publication types

  • Clinical Trial

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Blood Loss, Surgical
  • Dyspareunia / etiology
  • Fecal Incontinence / etiology
  • Female
  • Humans
  • Middle Aged
  • Pelvic Organ Prolapse / pathology
  • Pelvic Organ Prolapse / surgery*
  • Postoperative Complications / etiology*
  • Prosthesis Failure / etiology
  • Sexual Behavior
  • Surgical Mesh* / adverse effects
  • Surveys and Questionnaires
  • Time Factors
  • Treatment Outcome
  • Urinary Incontinence, Urge / etiology
  • Urinary Tract Infections / etiology
  • Vagina / pathology
  • Vagina / surgery