Use of sentinel node biopsy for staging parameningeal rhabdomyosarcoma

Pediatr Blood Cancer. 2011 Sep;57(3):520-3. doi: 10.1002/pbc.23052. Epub 2011 Feb 11.

Abstract

Identification of nodal involvement is important for treatment planning in patients with rhabdomyosarcoma, and is facilitated by sentinel node biopsy. Although it is employed primarily for extremity tumors, we report using sentinel node biopsy in a patient with parameningeal rhabdomyosarcoma arising in the ethmoid sinus. Lymphoscintigraphy with single photon emission computed tomography following injection of tracer at the tumor site helped identify contralateral cervical node involvement not previously recognized by physical exam, cross sectional imaging, or other functional imaging. This case demonstrates how information from sentinel node identification and biopsy can change therapy recommendations in patients with parameningeal rhabdomyosarcoma.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Combined Modality Therapy
  • Diagnostic Imaging / methods
  • Female
  • Humans
  • Lymph Nodes / pathology
  • Meningeal Neoplasms / diagnosis
  • Meningeal Neoplasms / pathology*
  • Neoplasm Staging
  • Rhabdomyosarcoma / diagnosis
  • Rhabdomyosarcoma / pathology*
  • Sentinel Lymph Node Biopsy* / methods
  • Treatment Outcome