Successful computer-based visual training specifically predicts visual memory enhancement over verbal memory improvement in schizophrenia

Schizophr Res. 2011 Nov;132(2-3):131-4. doi: 10.1016/j.schres.2011.06.031. Epub 2011 Jul 27.

Abstract

We investigated whether improved early visual processing on cognitive remediation (CR) exercises generalizes to visual and auditory learning and information manipulation in schizophrenia. Fourteen participants received neuropsychological testing before and after CR consisting of visual, auditory and cognitive control training. Achievement on visual training exercises was strongly and significantly correlated with improved visual learning, but not improved verbal learning or increased ability to manipulate visual information. Improvement in training, not training time, predicted cognitive gain. Implications for improving cognitive outcomes from CR include ensuring the trained task is learned and providing exercises of multiple modalities.

Trial registration: ClinicalTrials.gov NCT00339170.

Publication types

  • Clinical Trial
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Female
  • Humans
  • Male
  • Memory Disorders / etiology*
  • Memory Disorders / rehabilitation*
  • Middle Aged
  • Neuropsychological Tests
  • Photic Stimulation
  • Schizophrenia / complications*
  • Schizophrenia / rehabilitation
  • Therapy, Computer-Assisted*
  • Verbal Learning / physiology*
  • Visual Perception / physiology

Associated data

  • ClinicalTrials.gov/NCT00339170