Release of toxic ions from silver solder used in orthodontics: an in-situ evaluation

Am J Orthod Dentofacial Orthop. 2011 Aug;140(2):177-81. doi: 10.1016/j.ajodo.2010.06.024.

Abstract

Introduction: The objective of this study was to test the hypothesis that toxic metallic ions in silver solder used in orthodontics are released into saliva.

Methods: The sample included 60 children, 8 to 14 years of age, divided into 2 groups (n = 30 in each group): the control group and the study group (needing maxillary expansion with the hyrax appliance). For analysis of the release of metallic ions, saliva samples from each patient were collected at 6 times in both groups: before placement of the appliance and 10 minutes, 24 hours, and 7, 30, and 60 days after placement. The analysis of saliva was performed by atomic absorption spectrophotometry in a graphite oven to determine the concentrations of cadmium, copper, zinc, and silver ions. Statistical analyses were performed by the mixed model for repeated-measures covariance structure of the symmetrical component type, at P <0.05.

Results: The ion concentrations in the control group had low values for cadmium, copper, and zinc (P >0.05); for silver ions, the values did not reach the detection limit. In the study group, all ions showed expressive concentrations at 10 minutes after placement of the appliance (P <0.001), with the highest mean for copper (70.60 μg/L) and the lowest mean for zinc (0.07 μg/L). Comparison between groups revealed significant differences for copper (all periods), zinc (10 minutes, 24 hours, 7 and 30 days), and for cadmium only at 10 minutes.

Conclusions: Great amounts of these ions were released, with the highest concentrations immediately after placement of the appliance.

MeSH terms

  • Adolescent
  • Analysis of Variance
  • Cadmium / analysis
  • Case-Control Studies
  • Child
  • Copper / analysis
  • Dental Soldering / adverse effects*
  • Humans
  • Materials Testing
  • Orthodontic Appliances / adverse effects*
  • Palatal Expansion Technique / instrumentation*
  • Saliva / chemistry
  • Silver / analysis*
  • Spectrophotometry, Atomic
  • Zinc / analysis

Substances

  • Cadmium
  • Silver
  • Copper
  • Zinc