microRNAs as peripheral blood biomarkers of cardiovascular disease

Vascul Pharmacol. 2011 Oct;55(4):111-8. doi: 10.1016/j.vph.2011.08.001. Epub 2011 Aug 6.

Abstract

A host of studies have established essential roles for microRNAs in cardiovascular development and disease. Moreover, the discovery of stable microRNAs in bodily fluids indicated their potential as non-invasive biomarkers. In this review, we summarize the current studies describing microRNAs in blood cells or serum/plasma, as potential biomarkers of cardiovascular disease.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Biomarkers / blood
  • Blood Cells / metabolism
  • Cardiovascular Diseases / blood*
  • Cardiovascular Diseases / metabolism
  • Cardiovascular Diseases / physiopathology
  • Humans
  • MicroRNAs / blood*
  • MicroRNAs / metabolism

Substances

  • Biomarkers
  • MicroRNAs