Recent changes in nasopharyngeal flora of children in Japan

Tatsuya Hayashi; Tomoki Yoshizaki; Kenzo Ohara; Saeko Yoshida; Takumi Kumai; Yasuaki Harabuchi

doi:10.1159/000324789

Recent changes in nasopharyngeal flora of children in Japan

Adv Otorhinolaryngol. 2011:72:176-8. doi: 10.1159/000324789. Epub 2011 Aug 18.

Authors

Tatsuya Hayashi¹, Tomoki Yoshizaki, Kenzo Ohara, Saeko Yoshida, Takumi Kumai, Yasuaki Harabuchi

Affiliation

¹ Department of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University, Asahikawa, Hokkaido, Japan. thayashi@asahikawa-med.ac.jp

PMID: 21865722
DOI: 10.1159/000324789

Abstract

We investigated the relationship between nasopharyngeal flora of pediatric patients and antibiotic consumption in a local community in Japan between 2000 and 2009 retrospectively. There was a clear relationship between the lower annual consumption rate of cephalosporins and the lower annual prevalence of non-susceptible strains of Streptococcus pneumoniae (SP). High prevalence of BLNAR (β-lactamase nonproducing ampicillin-resistant Haemophilus influenzae) has been one of the bacteriological features of Japan.

Publication types

Comparative Study

MeSH terms

Anti-Bacterial Agents / therapeutic use*
Bacteria / drug effects*
Bacteria / isolation & purification
Child
Drug Resistance, Microbial*
Humans
Incidence
Japan / epidemiology
Microbial Sensitivity Tests
Nasopharynx / drug effects
Nasopharynx / microbiology*
Prognosis
Respiratory Tract Infections / drug therapy
Respiratory Tract Infections / epidemiology
Respiratory Tract Infections / microbiology*
Retrospective Studies

Substances

Anti-Bacterial Agents