On target? Tracing zinc-finger-nuclease specificity

Nat Methods. 2011 Aug 30;8(9):725-6. doi: 10.1038/nmeth.1680.

Abstract

In two independent studies, researchers experimentally test the cleavage specificity of zinc-finger nucleases across the genome.

Publication types

  • Comment

MeSH terms

  • DNA / metabolism*
  • Endodeoxyribonucleases / metabolism*
  • Humans
  • Substrate Specificity*
  • Zinc Fingers*

Substances

  • DNA
  • Endodeoxyribonucleases