Prevalence of beta-lactam nonsusceptible Gram-negative bacilli and use and interpretation of current susceptibility breakpoints: a survey of infectious disease physicians

Diagn Microbiol Infect Dis. 2011 Nov;71(3):316-9. doi: 10.1016/j.diagmicrobio.2011.07.013. Epub 2011 Sep 6.

Abstract

Beta-lactam-resistant Enterobacteriaceae represent an important public health problem; however, questions exist about their prevalence and the impact of recent breakpoint changes on clinical practice. We surveyed infectious disease physicians to better understand these issues. Many reported encountering resistant Enterobacteriaceae; respondents generally favored a more conservative interpretation of antimicrobial susceptibility results.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Anti-Bacterial Agents / therapeutic use
  • Drug Resistance, Multiple, Bacterial
  • Enterobacteriaceae / drug effects*
  • Enterobacteriaceae Infections / drug therapy
  • Enterobacteriaceae Infections / epidemiology*
  • Health Surveys
  • Humans
  • Microbial Sensitivity Tests
  • Physicians
  • Prevalence
  • Public Health
  • beta-Lactams / pharmacology*
  • beta-Lactams / therapeutic use

Substances

  • Anti-Bacterial Agents
  • beta-Lactams