General ultrasound screening reduces the rate of first operative procedures for developmental dysplasia of the hip: a case-control study

J Pediatr. 2012 Feb;160(2):271-5. doi: 10.1016/j.jpeds.2011.08.037. Epub 2011 Sep 29.

Abstract

Objectives: To assess the effectiveness of general ultrasound screening to prevent first operative procedures of the hip.

Study design: We conducted a case-control study in a population in which general ultrasound screening supplementing clinical screening is recommended and offered free of charge for all children. Participation in ultrasound screening before week 7 as recommended in Germany was the exposure of interest. Case ascertainment was based on active surveillance in orthopedic hospitals. The case definition was: first operative procedure for developmental dysplasia of the hip (closed reduction, open reduction, or osteotomy) in children >9 weeks old and <5 years old and born between 1996 and 2001. Control subjects from the same birth cohorts were recruited in telephone surveys.

Results: Cases of first operative procedures for developmental dysplasia of the hip (n = 446) were compared with 1173 control subjects for ultrasound screening. Effectiveness of ultrasound screening to prevent first operative procedures for developmental dysplasia of the hip was estimated as 52% (95% CI, 32-67). Effectiveness did not vary substantially for closed and open reductions and osteotomy.

Conclusions: General ultrasound screening reduces the rate of operative procedures for developmental dysplasia of the hip; the impact on developmental dysplasia of the hip. Treatment rates and avascular necrosis need further assessment to balance the benefit against potential overtreatment and adverse effects.

MeSH terms

  • Case-Control Studies
  • Child, Preschool
  • Female
  • Germany / epidemiology
  • Hip / abnormalities
  • Hip / diagnostic imaging*
  • Hip / surgery
  • Hip Dislocation, Congenital / diagnostic imaging*
  • Hip Dislocation, Congenital / epidemiology
  • Hip Dislocation, Congenital / surgery
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Male
  • Neonatal Screening / methods*
  • Orthopedic Procedures / statistics & numerical data*
  • Ultrasonography