A mutation of ispA that is involved in isoprenoid biogenesis can improve growth of Escherichia coli at low temperatures

Microbiol Immunol. 2011 Dec;55(12):885-8. doi: 10.1111/j.1348-0421.2011.00391.x.

Abstract

Cells lacking rodZ are defective not only in cell shape, but also in cell growth at low temperatures. Cold-sensitive growth was suppressed by a mutation of ispA without recovery from the round shape, and the mutation improved cell growth of the wild-type at low temperatures.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cold Temperature
  • Cytoskeletal Proteins / genetics
  • Cytoskeletal Proteins / metabolism
  • Escherichia coli / genetics
  • Escherichia coli / growth & development*
  • Escherichia coli Proteins / chemistry
  • Escherichia coli Proteins / genetics*
  • Escherichia coli Proteins / metabolism
  • Geranyltranstransferase
  • Mutation
  • Terpenes / metabolism*

Substances

  • Cytoskeletal Proteins
  • Escherichia coli Proteins
  • RodZ protein, E coli
  • Terpenes
  • Geranyltranstransferase
  • IspA protein, E coli