mTOR in podocyte function: is rapamycin good for diabetic nephropathy?

Cell Cycle. 2011 Oct 15;10(20):3415-6. doi: 10.4161/cc.10.20.17686.
No abstract available

Publication types

  • Editorial

MeSH terms

  • Animals
  • Diabetic Nephropathies / drug therapy*
  • Diabetic Nephropathies / metabolism
  • Mechanistic Target of Rapamycin Complex 1
  • Mice
  • Mice, Knockout
  • Monomeric GTP-Binding Proteins / metabolism
  • Multiprotein Complexes
  • Neuropeptides / metabolism
  • Podocytes / metabolism
  • Podocytes / physiology*
  • Proteins / antagonists & inhibitors
  • Proteins / metabolism*
  • Ras Homolog Enriched in Brain Protein
  • Signal Transduction / physiology*
  • Sirolimus / pharmacology*
  • Sirolimus / therapeutic use
  • TOR Serine-Threonine Kinases / metabolism*
  • Tuberous Sclerosis Complex 1 Protein
  • Tumor Suppressor Proteins / genetics
  • Tumor Suppressor Proteins / metabolism

Substances

  • Multiprotein Complexes
  • Neuropeptides
  • Proteins
  • Ras Homolog Enriched in Brain Protein
  • Rheb protein, mouse
  • Tuberous Sclerosis Complex 1 Protein
  • Tumor Suppressor Proteins
  • Mechanistic Target of Rapamycin Complex 1
  • TOR Serine-Threonine Kinases
  • Monomeric GTP-Binding Proteins
  • Sirolimus