Changes in tumor tissue organization in collagen-I sensitize cells to ionizing radiation in an ex vivo model of solid mammary tumor growth and local invasion

Cell Cycle. 2011 Nov 15;10(22):3979-81. doi: 10.4161/cc.10.22.18291. Epub 2011 Nov 15.
No abstract available

Publication types

  • Letter

MeSH terms

  • Animals
  • Apoptosis / drug effects
  • Apoptosis / radiation effects
  • Cell Shape / drug effects
  • Cell Shape / radiation effects
  • Collagen
  • Collagen Type I / metabolism
  • Collagen Type I / pharmacology*
  • Collagen Type I / physiology
  • Dasatinib
  • Drug Combinations
  • Female
  • Laminin
  • Mammary Neoplasms, Animal / genetics
  • Mammary Neoplasms, Animal / metabolism
  • Mammary Neoplasms, Animal / pathology*
  • Mice
  • Neoplasm Invasiveness / pathology
  • Protein Kinase Inhibitors / pharmacology
  • Proteoglycans
  • Pyrimidines / pharmacology
  • Radiation, Ionizing
  • Thiazoles / pharmacology
  • Tissue Culture Techniques

Substances

  • Collagen Type I
  • Drug Combinations
  • Laminin
  • Protein Kinase Inhibitors
  • Proteoglycans
  • Pyrimidines
  • Thiazoles
  • matrigel
  • Collagen
  • Dasatinib