Macular structure on optical coherence tomography after lamellar macular hole surgery and its correlation with visual outcome

Can J Ophthalmol. 2011 Dec;46(6):491-7. doi: 10.1016/j.jcjo.2011.09.011.

Abstract

Objective: To report macular structure on optical coherence tomography (OCT) after lamellar macular hole surgery and its relationship with visual outcome.

Design: Retrospective interventional case series; private practice setting.

Participants: Twelve patients diagnosed with a lamellar hole who had undergone vitrectomy and who had OCT scanning before and after surgery and at least 6 months follow-up were included.

Methods: Surgery consisted of 25 g vitrectomy, peeling of epiretinal and internal limiting membrane, fluid/air/gas exchange, and 2 weeks of face-down positioning.

Results: OCT showed an epiretinal membrane in all cases. After a mean follow-up of 16.7 months, VA improved by ≥2 lines in nine patients and remained stable in three. There was a complete closure of the lamellar hole in ten patients; in four a retinal pseudocyst was found during the healing process, resolving spontaneously in two and persisting in the other two after 8 and 9 months, respectively. Two patients developed a full-thickness macular hole that closed successfully after surgical repair. All patients had a VA ≥ 20/32 at the end of follow-up.

Conclusion: Epiretinal membranes appear to have a role in the pathogenesis of lamellar macular holes. Vitrectomy is a useful technique to obtain closure of the lamellar hole and visual improvement. The presence of a retinal pseudocyst is a common feature during the healing process and is compatible with a favorable visual outcome. A full-thickness macular hole is a severe and not uncommon complication of this procedure.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Basement Membrane / surgery
  • Endotamponade
  • Epiretinal Membrane / diagnosis
  • Epiretinal Membrane / physiopathology
  • Female
  • Fluorocarbons / administration & dosage
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Prone Position
  • Retinal Perforations / diagnosis*
  • Retinal Perforations / physiopathology
  • Retinal Perforations / surgery*
  • Retrospective Studies
  • Tomography, Optical Coherence*
  • Treatment Outcome
  • Visual Acuity / physiology*
  • Vitrectomy*

Substances

  • Fluorocarbons
  • perflutren