Rapid radiographic and clinical improvement after treatment of a MET-amplified recurrent glioblastoma with a mesenchymal-epithelial transition inhibitor

MeSH terms

• Brain Neoplasms / diagnostic imaging
• Brain Neoplasms / drug therapy*
• Brain Neoplasms / genetics
• Brain Neoplasms / pathology
• Crizotinib
• Epithelial-Mesenchymal Transition / drug effects*
• Female
• Gene Amplification
• Glioblastoma / diagnostic imaging
• Glioblastoma / drug therapy*
• Glioblastoma / genetics
• Glioblastoma / pathology
• Humans
• Middle Aged
• Proto-Oncogene Proteins c-met / genetics
• Pyrazoles / therapeutic use*
• Pyridines / therapeutic use*
• Radiography