High prevalence of metabolic syndrome in Iran in comparison with France: what are the components that explain this?

Metab Syndr Relat Disord. 2012 Jun;10(3):181-8. doi: 10.1089/met.2011.0097. Epub 2012 Jan 27.

Abstract

Background: The aim of this study was to investigate the difference in the prevalence of metabolic syndrome and its components between an Iranian and a French population.

Methods: The prevalence of metabolic syndrome, defined according to the Adult Treatment Panel III (ATP III), and of related abnormalities, was estimated in 1,386 French and 1,194 Iranian adults.

Results: The prevalence of metabolic syndrome was significantly higher in Iranian women (55.0%), followed by Iranian men (30.1%), than in French men (13.7%) and French women (6.6%). Iranian women were characterized by high rates of abdominal obesity (65.0%), hypertension (52.1%), hypertriglyceridemia (43.1%), and low high-density lipoprotein cholesterol (HDL-C; 92.7%). Iranian men were characterized by high rates of hypertension (48.9%), hypertriglyceridemia (42.8%), and low HDL-C (81.8%). French men had high rates of hypertension (44.7%) and mild rates of hypertriglyceridemia (28.6%) and hyperglycemia (23.9%). There was a relationship between waist circumference and the lipid components of metabolic syndrome in both countries.

Conclusion: The main finding of this study is the high prevalence of low HDL-C concentrations in the Iranian population, especially in Iranian women, compared with French women. Explanation of this observation could help in establishing prevention strategies.

Publication types

  • Comparative Study
  • Multicenter Study

MeSH terms

  • Adult
  • Analysis of Variance
  • Biomarkers / blood
  • Blood Glucose / analysis
  • Blood Pressure
  • Body Mass Index
  • Chi-Square Distribution
  • Cholesterol, HDL / blood
  • Cross-Cultural Comparison
  • Factor Analysis, Statistical
  • Female
  • France / epidemiology
  • Humans
  • Hyperglycemia / diagnosis
  • Hyperglycemia / epidemiology*
  • Hypertension / diagnosis
  • Hypertension / epidemiology*
  • Hypertriglyceridemia / diagnosis
  • Hypertriglyceridemia / epidemiology*
  • Iran / epidemiology
  • Male
  • Metabolic Syndrome / diagnosis
  • Metabolic Syndrome / epidemiology*
  • Middle Aged
  • Obesity, Abdominal / diagnosis
  • Obesity, Abdominal / epidemiology*
  • Prevalence
  • Sex Factors
  • Waist Circumference

Substances

  • Biomarkers
  • Blood Glucose
  • Cholesterol, HDL