The broad-leaf herbicide 2,4-dichlorophenoxyacetic acid turns rice into a living trap for a major insect pest and a parasitic wasp

New Phytol. 2012 Apr;194(2):498-510. doi: 10.1111/j.1469-8137.2012.04057.x. Epub 2012 Feb 7.

Abstract

Synthetic chemical elicitors of plant defense have been touted as a powerful means for sustainable crop protection. Yet, they have never been successfully applied to control insect pests in the field. We developed a high-throughput chemical genetics screening system based on a herbivore-induced linalool synthase promoter fused to a β-glucuronidase (GUS) reporter construct to test synthetic compounds for their potential to induce rice defenses. We identified 2,4-dichlorophenoxyacetic acid (2,4-D), an auxin homolog and widely used herbicide in monocotyledonous crops, as a potent elicitor of rice defenses. Low doses of 2,4-D induced a strong defensive reaction upstream of the jasmonic acid and ethylene pathways, resulting in a marked increase in trypsin proteinase inhibitor activity and volatile production. Induced plants were more resistant to the striped stem borer Chilo suppressalis, but became highly attractive to the brown planthopper Nilaparvata lugens and its main egg parasitoid Anagrus nilaparvatae. In a field experiment, 2,4-D application turned rice plants into living traps for N. lugens by attracting parasitoids. Our findings demonstrate the potential of auxin homologs as defensive signals and show the potential of the herbicide to turn rice into a selective catch crop for an economically important pest.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • 2,4-Dichlorophenoxyacetic Acid / toxicity*
  • Animals
  • Cyclopentanes / metabolism
  • Ethylenes / metabolism
  • Gene Expression Regulation, Plant / drug effects
  • Herbicides / toxicity*
  • Herbivory / drug effects
  • High-Throughput Screening Assays
  • Insecticide Resistance / drug effects
  • Mitogen-Activated Protein Kinases / genetics
  • Mitogen-Activated Protein Kinases / metabolism
  • Oryza / drug effects*
  • Oryza / enzymology
  • Oryza / genetics
  • Oryza / parasitology*
  • Oxylipins / metabolism
  • Pest Control*
  • Plant Leaves / drug effects*
  • Plant Leaves / parasitology
  • Plant Proteins / genetics
  • Plant Proteins / metabolism
  • RNA, Messenger / genetics
  • RNA, Messenger / metabolism
  • Salicylic Acid / metabolism
  • Trypsin Inhibitors / metabolism
  • Volatile Organic Compounds / metabolism
  • Wasps / drug effects*

Substances

  • Cyclopentanes
  • Ethylenes
  • Herbicides
  • Oxylipins
  • Plant Proteins
  • RNA, Messenger
  • Trypsin Inhibitors
  • Volatile Organic Compounds
  • 2,4-Dichlorophenoxyacetic Acid
  • jasmonic acid
  • ethylene
  • Mitogen-Activated Protein Kinases
  • Salicylic Acid