Linear dimensions and volumes of human lungs obtained from CT images

Health Phys. 2012 Apr;102(4):378-83. doi: 10.1097/HP.0b013e31823a13f1.

Abstract

This work provides the results of a collaboration between the Human Monitoring Laboratory (HML) and the Centre Hospitalier de l'Université de Montréal (CHUM) in which CHUM provided CT lung image sets from 166 patients for the analysis of linear dimensions and lung volume. This work has shown that a large amount of data exists in the medical community that can be of value to the health physics community. The intent of this study was to determine the range of linear dimensional parameters that could be used for torso phantom development for males and females; understand and characterize the variability of linear lung dimensions for males and females; replace the brief table in ICRP 23 with more modern data for males and females; identify an empirical formula that would predict linear dimensions of human lungs from age, height and/or weight for males and females; characterize the left, right, and total lung volumes of males and females in this data set; and compare the lung volumes of males and females to published equations for determining lung volumes. It was found that linear dimensions of lungs are essentially independent of age, height, and weight, so predictive equations cannot be formulated; however, the ranges of those parameters have now been established for the population studied herein. The data presented here are more modern than the brief table that appeared in ICRP 23, and the average values could be used as future guidelines. Whole lung volumes have been determined from the voxel lung phantoms, and empirical formulae have been developed for males and females in this data set; these compare favorably with the published values in ICRP 66.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Cooperative Behavior
  • Female
  • Humans
  • Image Processing, Computer-Assisted*
  • Linear Models
  • Lung / diagnostic imaging*
  • Lung / pathology*
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / pathology
  • Male
  • Middle Aged
  • Organ Size
  • Phantoms, Imaging
  • Tomography, X-Ray Computed*
  • Young Adult