A 59-year-old male underwent coronary artery bypass grafting and mitral ring annuloplasty 4 years ago. The procedure was complicated by sternal wound infection. Recently, he presented with multiple admissions for decompensated heart failure with volume overload and pulmonary edema. He was found to have severe mitral regurgitation (MR) and transesophageal echocardiography (TEE) demonstrated severe MR through an anterior mitral leaflet perforation. Due to high surgical risk, he was referred for transcatheter repair of his mitral valve. This case illustrates the first reported use of an Amplatzer atrial septal occluder device for percutaneous mitral leaflet repair using three-dimensional TEE guidance after prior surgical mitral ring annuloplasty repair.