Soft tissue sarcomas are rare malignant neoplasms accounting for only 1% of malignant tumors in adults. Complete surgical resection of tumors is the key to therapeutic success. Indications for adjuvant radiation therapy vary according to the lesion grade. Comprehensive diagnostic imaging significantly contributes to successful preoperative planning procedures. Besides morphological imaging, functional imaging strategies will have an increasing impact on individual risk assessment and contribute to optimized, non-invasive treatment response monitoring.