Abstract
The second scientific workshop of the European Crohn's and Colitis Organization (ECCO) focused on the relevance of intestinal healing for the disease course of inflammatory bowel disease (IBD). The objective was to better understand basic mechanisms, markers for disease prediction, detection and monitoring of intestinal healing, impact of intestinal healing on the disease course of IBD as well as therapeutic strategies. The results of this workshop are presented in four separate manuscripts. This section describes basic mechanisms of intestinal healing, identifies open questions in the field and provides a framework for future studies.
Copyright © 2011 European Crohn's and Colitis Organisation. Published by Elsevier B.V. All rights reserved.
MeSH terms
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Adrenal Cortex Hormones / pharmacology
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Anti-Bacterial Agents / pharmacology
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Anti-Inflammatory Agents, Non-Steroidal / pharmacology
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Antibodies, Monoclonal / pharmacology
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Azathioprine / pharmacology
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Butyric Acid / pharmacology
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Colitis, Ulcerative / genetics
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Colitis, Ulcerative / physiopathology*
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Crohn Disease / genetics
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Crohn Disease / physiopathology*
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Cyclosporine / pharmacology
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Defensins / physiology
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Extracellular Matrix / physiology
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Humans
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Immunosuppressive Agents / pharmacology
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Infliximab
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Intestinal Mucosa / pathology*
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Intestinal Mucosa / physiopathology*
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Leptin / physiology
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Matrix Metalloproteinases / physiology
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Mesalamine / pharmacology
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Paneth Cells / physiology
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Probiotics / pharmacology
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Reactive Nitrogen Species / physiology
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Reactive Oxygen Species / metabolism
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Sulfasalazine / pharmacology
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Tumor Necrosis Factor-alpha / physiology
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Wound Healing / drug effects*
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Wound Healing / physiology*
Substances
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Adrenal Cortex Hormones
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Anti-Bacterial Agents
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Anti-Inflammatory Agents, Non-Steroidal
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Antibodies, Monoclonal
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Defensins
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Immunosuppressive Agents
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Leptin
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Reactive Nitrogen Species
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Reactive Oxygen Species
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Tumor Necrosis Factor-alpha
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Butyric Acid
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Sulfasalazine
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Mesalamine
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Cyclosporine
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Infliximab
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Matrix Metalloproteinases
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Azathioprine