Polymer pen lithography (PPL)-induced site-specific click chemistry for the formation of functional glycan arrays

Shudan Bian; Jiajun He; Kevin B Schesing; Adam B Braunschweig

doi:10.1002/smll.201102707

Polymer pen lithography (PPL)-induced site-specific click chemistry for the formation of functional glycan arrays

Small. 2012 Jul 9;8(13):2000-5. doi: 10.1002/smll.201102707. Epub 2012 Apr 10.

Authors

Shudan Bian¹, Jiajun He, Kevin B Schesing, Adam B Braunschweig

Affiliation

¹ Department of Chemistry and The Molecular Design Institute, New York University, 100 Washington Square East, New York, NY 10003, USA.

PMID: 22488791
DOI: 10.1002/smll.201102707

Abstract

Polymer pen lithography (PPL) can be combined with the Cu(I) -catalyzed azide-alkyne click reaction to create molecular arrays with control over orientation and sub-1 μm feature sizes over cm(2) areas. The process has been applied to the deposition of carbohydrates to form functional glycochips.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Carbohydrates / chemistry*
Click Chemistry / methods*
Polymers / chemistry*

Substances

Carbohydrates
Polymers