[The relationship between oxidative stress and obesity in prostate disease]

Urologia. 2012 Apr-Jun;79(2):156-8. doi: 10.5301/RU.2012.9206.
[Article in Italian]

Abstract

Recent data suggest that chronic increment of reactive oxygen species (ROS) may be involved in the development and progression of chronic prostatic disease, such as BPH and PCa; adipose tissue produces bioactive substances called adipokines, also involved in the production of ROS. Our study aims to evaluate the relationship between obesity and oxidative stress in prostate disease.

Publication types

  • English Abstract

MeSH terms

  • Adenocarcinoma / chemistry
  • Adenocarcinoma / complications*
  • Adipokines / metabolism
  • Adipose Tissue / metabolism
  • Adiposity
  • Aged
  • Biopsy
  • Body Mass Index
  • Disease Progression
  • Glutathione / analysis
  • Humans
  • Male
  • Middle Aged
  • Obesity / complications*
  • Obesity / metabolism
  • Organ Size
  • Oxidative Stress*
  • Plethysmography, Whole Body
  • Prostate / chemistry
  • Prostate / pathology
  • Prostate-Specific Antigen / analysis
  • Prostatic Hyperplasia / complications*
  • Prostatic Hyperplasia / metabolism
  • Prostatic Neoplasms / chemistry
  • Prostatic Neoplasms / complications*
  • Prostatitis / complications*
  • Prostatitis / metabolism
  • Reactive Oxygen Species / metabolism

Substances

  • Adipokines
  • Reactive Oxygen Species
  • Prostate-Specific Antigen
  • Glutathione