Evaluation of a rapid point-of-care fecal antigen detection test for Entamoeba histolytica

Am J Trop Med Hyg. 2012 Jun;86(6):980-1. doi: 10.4269/ajtmh.2012.11-0661.

Abstract

Amebiasis is a major cause of morbidity and mortality in the developing world. A reliable point-of-care test would help to improve diagnosis and early treatment. We evaluated a novel rapid fecal antigen detection test for E. histolytica (E. HISTOLYTICA QUIK CHEK; TechLab, Inc., Blacksburg, VA), in a cohort of children in Bangladesh where amebiasis is endemic. This point-of-care test had a sensitivity of 100% and a specificity of 100% when compared with enzyme-linked immunosorbent assay antigen detection.

Publication types

  • Evaluation Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Amebiasis / diagnosis*
  • Amebiasis / epidemiology*
  • Antigens, Protozoan / isolation & purification*
  • Bangladesh / epidemiology
  • Child
  • Child, Preschool
  • Entamoeba histolytica / isolation & purification*
  • Enzyme-Linked Immunosorbent Assay
  • Feces / parasitology
  • Humans
  • Infant
  • Point-of-Care Systems*
  • Sensitivity and Specificity
  • Specimen Handling

Substances

  • Antigens, Protozoan