Preventing platelet thrombosis with a PAR1 pepducin

Circulation. 2012 Jul 3;126(1):13-5. doi: 10.1161/CIRCULATIONAHA.112.122317. Epub 2012 Jun 15.
No abstract available

Publication types

  • Editorial
  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Blood Platelets / drug effects
  • Blood Platelets / metabolism*
  • Humans
  • Lipopeptides / pharmacology
  • Lipopeptides / therapeutic use
  • Platelet Aggregation Inhibitors / pharmacology
  • Platelet Aggregation Inhibitors / therapeutic use
  • Receptor, PAR-1 / antagonists & inhibitors
  • Receptor, PAR-1 / metabolism*
  • Signal Transduction / drug effects
  • Signal Transduction / physiology
  • Thrombosis / blood
  • Thrombosis / prevention & control*

Substances

  • F2pal-16 pepducin
  • Lipopeptides
  • Platelet Aggregation Inhibitors
  • Receptor, PAR-1