Investigation of higher-order cognitive functions during exposure to a high static magnetic field

J Magn Reson Imaging. 2012 Oct;36(4):835-40. doi: 10.1002/jmri.23727. Epub 2012 Jun 21.

Abstract

Purpose: To test for potential changes in higher-order cognitive processes related to the exposure to a high static magnetic field.

Materials and methods: Twenty-four healthy volunteers participated in two experimental sessions inside a 3 Tesla (T) magnetic resonance imaging (MRI) magnet. During one session the magnetic field was ramped down. The tasks consisted of six well-established paradigms probing a variety of cognitive functions. Reaction times (RT) and accuracies (AC) were recorded for statistical analysis.

Results: The overall performance was very similar in both sessions. Strong task-specific effects (all P < 0.006) were consistent with previously published results. Direct comparisons of task-specific effects between the two sessions (magnetic field on or off) remained insignificance for all paradigms (RT: all P > 0.196; AC: all P > 0.17; no corrections for multiple comparisons).

Conclusion: The results did not indicate any apparent safety concerns with respect to cognitive performance in a static magnetic field of a typical whole-body magnet. In addition, comparisons of cognitive effects from testing situations with and without exposure to high static magnetic fields can be considered valid.

MeSH terms

  • Adult
  • Brain / physiology*
  • Brain / radiation effects*
  • Cognition / physiology*
  • Cognition / radiation effects*
  • Dose-Response Relationship, Radiation
  • Female
  • Humans
  • Magnetic Fields*
  • Magnetic Resonance Imaging*
  • Male
  • Radiation Dosage
  • Task Performance and Analysis*
  • Young Adult