Transventricular balloon dilation and stenting of the RVOT in small infants with tetralogy of fallot with pulmonary atresia

Catheter Cardiovasc Interv. 2013 Aug 1;82(2):260-5. doi: 10.1002/ccd.24548. Epub 2013 Apr 5.

Abstract

Introduction: The management of small infants with tetralogy of Fallot (TOF) with pulmonary atresia (PA) and hypoplastic pulmonary arteries can be very challenging.

Methods: In three small infants (weight range 2,200-3,600 g, pulmonary trunk 2.0-3.2 mm), initial palliation consisted of sternotomy, transventricular puncture of the right ventricular outflow tract and atretic pulmonary valve, followed by balloon dilation (n = 1) or stent deployment (n = 2) from the right ventricle into the pulmonary trunk (stent diameter 5-6 mm, length 16 mm).

Results: The procedure resulted in adequate palliation with good anterograde flow to the pulmonary arteries and near normal saturations in all three patients (>92%); there was no associated morbidity. Additional transvenous stenting was required in all patients because of progressive muscular infundibular stenosis after a median of 3 months. Two patients evolved to full repair at the age of 5 months and one patient with multiple hilar stenoses requires additional percutaneous procedures through the stented RV outflow tract.

Conclusion: Transventricular balloon dilation and stenting of the RVOT through medial sternotomy as initial palliation strategy appears a safe and well tolerated alternative treatment in small infants with TOF with PA and a hypoplastic pulmonary trunk.

Keywords: congenital heart disease; hybrid procedure; palliation; perventricular; premature infant; pulmonary atresia; small infant; stenting; tetralogy of Fallot; transventricular.

MeSH terms

  • Abnormalities, Multiple*
  • Cardiac Catheterization / instrumentation*
  • Coronary Circulation
  • Gestational Age
  • Humans
  • Infant, Low Birth Weight*
  • Infant, Newborn
  • Infant, Premature
  • Palliative Care
  • Pulmonary Atresia / diagnosis
  • Pulmonary Atresia / physiopathology
  • Pulmonary Atresia / therapy*
  • Pulmonary Circulation
  • Punctures
  • Radiography, Interventional
  • Stents*
  • Sternotomy
  • Tetralogy of Fallot / diagnosis
  • Tetralogy of Fallot / physiopathology
  • Tetralogy of Fallot / therapy*
  • Treatment Outcome
  • Ventricular Outflow Obstruction / diagnosis
  • Ventricular Outflow Obstruction / physiopathology
  • Ventricular Outflow Obstruction / therapy*