GATA2 mutations are frequent in intermediate-risk karyotype AML with biallelic CEBPA mutations and are associated with favorable prognosis

Leukemia. 2013 Feb;27(2):482-5. doi: 10.1038/leu.2012.174. Epub 2012 Jul 3.
No abstract available

Publication types

  • Letter

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Alleles
  • CCAAT-Enhancer-Binding Proteins / genetics*
  • Female
  • GATA2 Transcription Factor / genetics*
  • Humans
  • Karyotyping
  • Leukemia, Myeloid, Acute / genetics*
  • Leukemia, Myeloid, Acute / mortality
  • Leukemia, Myeloid, Acute / therapy
  • Male
  • Middle Aged
  • Mutation / genetics*
  • RNA, Messenger / genetics
  • Real-Time Polymerase Chain Reaction
  • Reverse Transcriptase Polymerase Chain Reaction
  • Young Adult

Substances

  • CCAAT-Enhancer-Binding Proteins
  • CEBPA protein, human
  • GATA2 Transcription Factor
  • GATA2 protein, human
  • RNA, Messenger