Prostate T.C.T. is a rare tumour representing about 1% of all prostate tumours. Out of 435 patients diagnosed in our prostate cancer service between 1975 and 1988, only 2 presented the features of transitional carcinoma of prostatic ductus coexisting in both cases with a glandular type tumour (0.45%). Both cases were treated in a palliative way through R.T.U. and hormonotherapy, also performing in one case telecobalto-therapy. The two cases presented had a very poor evolution, and die 6 month after diagnosis due to tumoral progression with a widespread bone metastasis, blastic in one case and mixed in the other one.