Usefulness of 3D DSA-MR fusion imaging in the pretreatment evaluation of brain arteriovenous malformations

Acad Radiol. 2012 Nov;19(11):1345-52. doi: 10.1016/j.acra.2012.07.001. Epub 2012 Aug 28.

Abstract

Rationale and objectives: For the evaluation of patients scheduled for the treatment of brain arteriovenous malformations (AVMs), accurate anatomical information is essential. The purpose of this study was to assess the usefulness of three-dimensional (3D) digital subtraction angiography (DSA)-magnetic resonance (MR) fusion imaging for the pretreatment evaluation of AVMs.

Materials and methods: The study population consisted of 11 consecutive patients (7 males, 4 females; age 10-72 years; mean 45 years) with brain AVMs. All prospectively underwent pretreatment MR imaging (MRI), MR angiography (MRA), and two-dimensional (2D) and 3D DSA. The 3D DSA and MR images were semiautomatically fused with fusion software on a workstation. In the delineation of AVM nidus, feeder, drainer, and relationship between AVM and the adjacent brain structures, two radiologists independently evaluated MRA and MRI, three-dimensional (3D) DSA, and MRI, and 3D DSA-MR fusion images using a 4-point scoring system. The referring neurosurgeons were asked whether the information provided by 3D DSA-MR fusion images was helpful for treatment decisions.

Results: For all four items, the delineation was significantly better with the 3D DSA/MRI or 3D DSA-MR fusion images than the MRA/MRI images. Although the delineation for the nidus, feeder, and drainer were not significantly different between the 3D DSA/MRI and 3D DSA-MR fusion images, 3D DSA-MR fusion imaging were significantly better for the relationship between AVM and the adjacent brain structures than 3D DSA/MR imaging (P = .0047). The information provided by 3D DSA-MR fusion images was helpful for treatment decisions in all cases.

Conclusion: 3D DSA-MR fusion images are useful for the pretreatment evaluation of brain AVMs.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Algorithms
  • Angiography, Digital Subtraction / methods*
  • Cerebral Angiography / methods*
  • Child
  • Female
  • Humans
  • Image Enhancement / methods
  • Image Interpretation, Computer-Assisted / methods*
  • Imaging, Three-Dimensional / methods*
  • Intracranial Arteriovenous Malformations / diagnosis*
  • Intracranial Arteriovenous Malformations / surgery
  • Magnetic Resonance Imaging / methods*
  • Male
  • Middle Aged
  • Preoperative Care / methods
  • Prognosis
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Subtraction Technique*
  • Young Adult