The application of CT to localize the upper airway obstruction plane in patients with OSAHS

Otolaryngol Head Neck Surg. 2012 Dec;147(6):1148-53. doi: 10.1177/0194599812459461. Epub 2012 Sep 5.

Abstract

Objective: To identify a correlation in terms of airway obstruction between awake and sleep apnea using spiral computed tomography (CT).

Study design: Case series with planned data collection.

Setting: College medical center.

Methods: Sixty-one patients diagnosed with obstructive sleep apnea/hypopnea syndrome (OSAHS) underwent CT scans under 3 conditions: quiet breathing while awake, the end of deep inspiration during wakefulness, and apnea while asleep. The upper airway morphology under the 3 conditions was compared, and the accuracy of the obstructive planes as determined by CT scans under the 2 awake conditions was analyzed while considering the obstructive planes that occurred during apnea as a reference.

Results: The differences in the anteroposterior diameter, lateral dimension, and cross-sectional area of the retropalatal and retroglossal regions among the 3 states were statistically significant. Obstruction of the retropalatal region occurred in 100%, whereas retroglossal obstruction occurred in 44.3% of the 61 cases during sleep apnea. The coincidence rate between the awake quiet breathing and the sleep apnea was 85.2% in the retropalatal obstruction and 52.5% in the retroglossal obstruction. The coincidence rate between the awake deep inspiration and the sleep apnea was 82.0% in the retropalatal obstruction and 54.1% in the retroglossal obstruction.

Conclusion: The main obstructive plane in patients with OSAHS was the retropalatal region. An awake upper airway CT scan can properly diagnose palatopharyngeal obstruction; however, it is not suitable for detecting retroglossal obstruction.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Airway Obstruction / diagnostic imaging*
  • Airway Obstruction / etiology
  • Airway Obstruction / physiopathology
  • Female
  • Humans
  • Inhalation / physiology
  • Male
  • Middle Aged
  • Oropharynx / diagnostic imaging
  • Sleep Apnea, Obstructive / diagnostic imaging*
  • Sleep Apnea, Obstructive / etiology
  • Sleep Apnea, Obstructive / physiopathology
  • Tomography, Spiral Computed*
  • Wakefulness*