Primary cutaneous aggressive epidermotropic CD4/CD8 double-negative cytotoxic T-cell lymphoma

Pathologica. 2012 Apr;104(2):78-81.

Abstract

The classification of cutaneous T-cell lymphomas (CTCL) is based on clinical, histological and immunohistochemical findings. Diagnosis may be difficult given the significant heterogeneity of these tumours. We describe herein an original case of primary cutaneous aggressive epidermotropic CD4/CD8 double-negative cytotoxic T-cell lymphoma that illustrates the difficulty in classification.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • CD4-Positive T-Lymphocytes / pathology
  • CD8-Positive T-Lymphocytes / pathology
  • Epidermis / immunology
  • Epidermis / pathology*
  • Female
  • Humans
  • Lymphoma, T-Cell / immunology
  • Lymphoma, T-Cell / pathology*
  • Skin Neoplasms / immunology
  • Skin Neoplasms / pathology*
  • T-Lymphocytes, Cytotoxic / pathology*