Detecting and managing hereditary colorectal cancer syndromes in your practice

Cleve Clin J Med. 2012 Nov;79(11):787-96. doi: 10.3949/ccjm.79a.11165.

Abstract

Hereditary syndromes account for 5% to 10% of cases of colorectal cancer. In clinical practice, patients with these syndromes need to be identified to ensure that they and their families receive genetic counseling and testing and appropriate risk-reducing treatment. Genetic testing can offer a precise diagnosis. It allows for risk stratification and focused management and surveillance.

MeSH terms

  • Adenoma / diagnosis
  • Adenomatous Polyposis Coli* / diagnosis
  • Adenomatous Polyposis Coli* / genetics
  • Adenomatous Polyposis Coli* / prevention & control
  • Adenomatous Polyposis Coli* / therapy
  • Age of Onset
  • Colorectal Neoplasms, Hereditary Nonpolyposis* / diagnosis
  • Colorectal Neoplasms, Hereditary Nonpolyposis* / genetics
  • Colorectal Neoplasms, Hereditary Nonpolyposis* / prevention & control
  • Colorectal Neoplasms, Hereditary Nonpolyposis* / therapy
  • Family Health
  • Genetic Counseling / methods
  • Genetic Counseling / standards*
  • Genetic Predisposition to Disease*
  • Genetic Testing / standards*
  • Humans