A girl with difficult lupus nephritis: lupus vasculopathy

Clin Exp Nephrol. 2012 Dec;16(6):968-72. doi: 10.1007/s10157-012-0720-5. Epub 2012 Nov 9.

Abstract

Lupus vasculopathy (LV) is one of the complications of lupus nephritis. No definite therapy has been recommended for the management of LV, and patient outcomes are variable. We present the case of a 16-year-old girl who recovered from stage V chronic kidney disease due to lupus nephritis with vasculopathy with active treatment including pulse methylprednisolone, cyclophosphamide, rituximab and plasma exchange.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Antibodies, Monoclonal, Murine-Derived / therapeutic use
  • Cyclophosphamide / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Lupus Nephritis / complications*
  • Methylprednisolone / therapeutic use
  • Plasma Exchange
  • Renal Insufficiency, Chronic / etiology*
  • Renal Insufficiency, Chronic / therapy*
  • Rituximab
  • Severity of Illness Index*
  • Treatment Outcome
  • Vascular Diseases / complications*
  • Vascular Diseases / etiology

Substances

  • Antibodies, Monoclonal, Murine-Derived
  • Immunosuppressive Agents
  • Rituximab
  • Cyclophosphamide
  • Methylprednisolone