Forever young? Exploring the link between rapamycin, longevity and cancer

Cell Cycle. 2012 Dec 1;11(23):4296-7. doi: 10.4161/cc.22868. Epub 2012 Nov 14.
No abstract available

Publication types

  • Editorial

MeSH terms

  • Animals
  • Antineoplastic Agents / therapeutic use*
  • Disease Progression
  • Longevity*
  • Mice
  • Mice, Knockout
  • Neoplasms / drug therapy*
  • Neoplasms / metabolism
  • Neoplasms / pathology
  • Signal Transduction
  • Sirolimus / therapeutic use*
  • TOR Serine-Threonine Kinases / antagonists & inhibitors
  • TOR Serine-Threonine Kinases / metabolism
  • Tumor Suppressor Protein p53 / deficiency
  • Tumor Suppressor Protein p53 / genetics
  • Tumor Suppressor Protein p53 / metabolism

Substances

  • Antineoplastic Agents
  • Tumor Suppressor Protein p53
  • TOR Serine-Threonine Kinases
  • Sirolimus