Abstract
We describe the first isolation in France of a New-Delhi metallo-beta-lactamase-1 (NDM-1) producing Pseudomonas aeruginosa. In March 2012, a patient with history of prior hospitalisation in Serbia was diagnosed in France with acute pyelonephritis due to NDM-1 producing P. aeruginosa. Clinical and microbiological cure was obtained under appropriate antibiotic treatment. Two months later, she presented with a recurrence due to the same bacteria, with a favourable evolution. During both hospitalisations, contact isolation precautions were implemented and no cross-transmission was observed.
MeSH terms
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Acute Disease
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Anti-Bacterial Agents / pharmacology
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Anti-Bacterial Agents / therapeutic use
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Drug Resistance, Multiple, Bacterial
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Female
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France
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Hospitalization
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Humans
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Klebsiella Infections / microbiology
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Microbial Sensitivity Tests
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Middle Aged
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Pseudomonas Infections / drug therapy
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Pseudomonas Infections / microbiology*
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Pseudomonas aeruginosa / drug effects
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Pseudomonas aeruginosa / genetics*
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Pseudomonas aeruginosa / isolation & purification
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Pyelonephritis / drug therapy
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Pyelonephritis / microbiology*
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Recurrence
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Serbia
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Travel*
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Urinary Catheterization / adverse effects
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Urinary Tract Infections / microbiology
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Urinary Tract Infections / prevention & control
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beta-Lactam Resistance / drug effects
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beta-Lactamases / genetics*
Substances
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Anti-Bacterial Agents
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beta-Lactamases
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beta-lactamase NDM-1