Passive cooling during transport of asphyxiated term newborns

J Perinatol. 2013 Jun;33(6):435-40. doi: 10.1038/jp.2012.138. Epub 2012 Nov 15.

Abstract

Objective: To evaluate the efficacy and safety of passive cooling during transport of asphyxiated newborns.

Study design: Retrospective medical record review of newborns with perinatal asphyxia transported for hypothermia between July 2007 and June 2010.

Result: Of 43 newborns transported, 27 were passively cooled without significant adverse events. Twenty (74%) passively cooled newborns arrived with temperature between 32.5 and 34.5 °C. One newborn arrived with a temperature <32.5, and 6 (22%) had temperatures >34.5 °C. Time from birth to hypothermia was significantly shorter among passively cooled newborns compared with newborns not cooled (215 vs 327 min, P<0.01), even though time from birth to admission to Boston Children's Hospital was similar (252 vs 259 min, P=0.77). Time from birth to admission was the only significant predictor of increased time to reach target temperature (P=0.001).

Conclusion: Exclusive passive cooling achieves significantly earlier initiation of effective hypothermia for asphyxiated newborns but should not delay transport for active cooling.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Apgar Score
  • Asphyxia Neonatorum / diagnosis
  • Asphyxia Neonatorum / therapy*
  • Birth Weight
  • Body Temperature
  • Electroencephalography
  • Female
  • Gestational Age
  • Humans
  • Hypothermia, Induced / methods*
  • Hypoxia-Ischemia, Brain / prevention & control
  • Infant, Newborn
  • Intensive Care Units, Neonatal
  • Male
  • Neurologic Examination
  • Patient Outcome Assessment
  • Prognosis
  • Retrospective Studies
  • Transportation of Patients*