Abstract
Another new substance from the family of Pt-based coordination complexes with potential use in cancer chemotherapy has been synthesized, crystallized and structurally characterized. In this compound {systematic name cis-dibromido[(1R,2R)-cyclohexane-1,2-diamine-κ(2)N,N']platinum(II)}, cis-[PtBr(2)(C(6)H(14)N(2))], there are two molecules with very similar conformations in the asymmetric unit. The component species interact by way of N-H...Br and C-H...Br hydrogen bonds to give two-dimensional networks which lie parallel to the (100) plane.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Antineoplastic Agents / chemical synthesis*
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Antineoplastic Agents / chemistry*
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Antineoplastic Agents / pharmacology
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Crystallography, X-Ray
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Cyclohexanes / chemistry*
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Cytostatic Agents / chemical synthesis*
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Cytostatic Agents / chemistry*
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Cytostatic Agents / pharmacology
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Diamines / chemistry*
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Mice
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Molecular Conformation
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Neoplasms / chemistry*
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Neoplasms / drug therapy
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Organoplatinum Compounds / chemical synthesis*
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Organoplatinum Compounds / chemistry*
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Organoplatinum Compounds / pharmacology
Substances
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Antineoplastic Agents
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Cyclohexanes
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Cytostatic Agents
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Diamines
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Organoplatinum Compounds
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cis-dibromido((1R,2R)-cyclohexane-1,2-diamine-kappa(2)N,N')platinum(II)
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Cyclohexane