ADAMTS13 antibody depletion by bortezomib in thrombotic thrombocytopenic purpura

N Engl J Med. 2013 Jan 3;368(1):90-2. doi: 10.1056/NEJMc1213206.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • ADAM Proteins / immunology*
  • ADAMTS13 Protein
  • Autoantibodies / blood*
  • B-Lymphocytes / drug effects*
  • Boronic Acids / pharmacology
  • Boronic Acids / therapeutic use*
  • Bortezomib
  • Female
  • Humans
  • Immunosuppressive Agents / therapeutic use
  • Middle Aged
  • Plasma Cells / drug effects*
  • Protease Inhibitors / pharmacology
  • Protease Inhibitors / therapeutic use*
  • Purpura, Thrombotic Thrombocytopenic / drug therapy
  • Purpura, Thrombotic Thrombocytopenic / immunology*
  • Pyrazines / pharmacology
  • Pyrazines / therapeutic use*

Substances

  • Autoantibodies
  • Boronic Acids
  • Immunosuppressive Agents
  • Protease Inhibitors
  • Pyrazines
  • Bortezomib
  • ADAM Proteins
  • ADAMTS13 Protein
  • ADAMTS13 protein, human